Toxicity Profile of Intensity Modulated Radiotherapy Vs. 3D-Conformal Radiotherapy in Head and neck cancer: A Retrospective study

Background: Most head and neck patients have historically been treated with photon-based radiation techniques such as intensity modulated therapy (IMRT), there is a growing awareness of the potential clinical benefits proton over IMRT in definitive, postoperative reirradiation settings given unique physical properties protons. Aim work: to assess toxicity profile comparison 3D conformal radiotherapy (3DCRT) predictors for progression free survival overall rates. Patients Methods: This retrospective cohort study included 131 cancer who were recruited from El Hussein University Hospital 10 years then they divided into 2 groups according type radiotherapy. Results: Both comparable regarding age, sex associated medical disorders except ischemic heart disease smoking. Sites primary tumors tongue nasopharynx. 3DCRT group received TPF induction chemotherapy most concurrent chemotherapy. Dose irradiation was higher significantly among group. Grades early late There no statistically significant difference between both response treatment. Mortality cases Cox regression analysis performed each Conclusion: provide good choice technique cancers adequate efficacy similar other better profile.